HIV Replication in LEGO Mosaic.

FIG. 1. The image shows the HIV replication cycle, illustrated in LEGO mosaic. A full movie in stop action LEGO can be viewed at www.bushmanlab.org/lego. The video displays how the HIV virus binds to cells, how preintegration complexes enter the nucleus, how HIV DNA becomes integrated into human DNA, and how HIV particles assemble. The movie was made using frames made of LEGO pieces, which were rearranged in between photos. The video was made to explain the process to younger children, and also as a way to generate interest in the topic.